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Merck

BP907

Acetylcysteine

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

N-Acetyl-L-cysteine, LNAC, NAC

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About This Item

Linear Formula:
HSCH2CH(NHCOCH3)CO2H
CAS Number:
616-91-1
Molecular Weight:
163.19
EC Number:
210-498-3
UNSPSC Code:
12352209
NACRES:
NA.24
Beilstein/REAXYS Number:
1724426
MDL number:
MFCD00004880

Key Documents

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InChI key

PWKSKIMOESPYIA-BYPYZUCNSA-N

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

SMILES string

CC(=O)N[C@@H](CS)C(O)=O

grade

pharmaceutical primary standard

API family

acetylcysteine

form

crystalline

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

106-108 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

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Related Categories

Application

Acetylcysteine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Acetylcysteine Eye Drops

    • Biochem/physiol Actions

    Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

    General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.

    Packaging

    Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    pictograms

    Exclamation mark
    GHS07

    signalword

    Warning

    hcodes

    H319

    Hazard Classifications

    Eye Irrit. 2

    Storage Class

    13 - Non Combustible Solids

    wgk

    WGK 2

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

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    Hongge Wang et al.
    Oncogene, 39(14), 2905-2920 (2020-02-08)
    PARP1 and PARP2 play critical roles in regulating DNA repair and PARP inhibitors have been approved for the treatment of BRCA1/2-mutated ovarian and breast cancers. It has long been known that PARP inhibition sensitizes cancer cells to DNA-damaging cytotoxic agents

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