T4562
Thiamine hydrochloride
meets USP testing specifications
Synonym(s):
Aneurine hydrochloride, Vitamin B1 hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C12H17ClN4OS · HCl
CAS Number:
Molecular Weight:
337.27
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
34058006
UNSPSC Code:
12352116
EC Number:
200-641-8
MDL number:
Beilstein/REAXYS Number:
3851771
biological source
synthetic (organic)
Quality Level
agency
USP/NF, meets USP testing specifications
assay
98.0-102.0%
form
solid
mp
250 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
SMILES string
CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
InChI
1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
InChI key
DPJRMOMPQZCRJU-UHFFFAOYSA-M
Application
Required to support energy metabolism and amino acid synthesis in cultured cells. Present in many classical and serum-free formulations.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Joseph E Kerschner et al.
Archives of otolaryngology--head & neck surgery, 135(1), 33-39 (2009-01-21)
To investigate genetic differences in middle ear mucosa (MEM) with nontypeable Haemophilus influenzae (NTHi) infection. Genetic upregulation and downregulation occurs in MEM during otitis media (OM) pathogenesis. A comprehensive assessment of these genetic differences using the techniques of complementary DNA
Samir Ahmed El-Shazly et al.
International journal of immunopathology and pharmacology, 28(2), 227-239 (2015-03-31)
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia due to abnormalities in either insulin secretion or action. A range of vanadium complexes have been synthesized and demonstrated to be effective in lowering hyperglycemia. Thiamine administration was also
Kris Niño G Valdehuesa et al.
Bioprocess and biosystems engineering, 38(9), 1761-1772 (2015-06-07)
Biosynthetic pathways for the production of biofuels often rely on inherent aldehyde reductases (ALRs) of the microbial host. These native ALRs play vital roles in the success of the microbial production of 1,3-propanediol, 1,4-butanediol, and isobutanol. In the present study