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About This Item
NACRES:
NA.47
UNSPSC Code:
41116124
form
solution
IVD
for in vitro diagnostic use
concentration
2.4 g/L
application(s)
hematology
histology
shipped in
dry ice
storage temp.
−20°C
Quality Level
Related Categories
Application
Intended for use in the Sigma α-Butyrate Esterase kit, procedure 181B
Packaging
2.4g/L alpha-naphthyl butyrate in methanol solution with stabilizers
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - STOT SE 1
target_organs
Eyes,Central nervous system
wgk
WGK 3
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Michael D'Angelica et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(9), 1221-1228 (2011-05-17)
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The human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein repressed the transcriptional activity of wild-type p53 through its N-terminal trans-activation domain. Although Tax did not directly bind to p53, this repression required the activation of CREB pathway by Tax.
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The p53 gene is rarely mutated in neuroblastoma, but codon 72 polymorphism that modulates its proapoptotic activity might influence cancer risk and clinical outcome. We investigated whether this polymorphism affects neuroblastoma risk and disease outcome and assessed the biologic effects
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COP1 (constitutively photomorphogenic 1) is a RING-finger-containing protein that functions to repress plant photomorphogenesis, the light-mediated programme of plant development. Mutants of COP1 are constitutively photomorphogenic, and this has been attributed to their inability to negatively regulate the proteins LAF1
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