Skip to Content
Merck

A138

Aminobenztropine

solid

Synonym(s):

3-(2′-Aminobenzhydryloxy)tropane, ABT

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C21H26N2O
CAS Number:
88097-86-3
Molecular Weight:
322.44
NACRES:
NA.77
PubChem Substance ID:
24277819
UNSPSC Code:
12352200
MDL number:
MFCD00078565
Form:
solid
Quality level:
100

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

solid

Quality Level

100

color

white

solubility

0.1 M HCl: soluble, 0.1 M NaOH: insoluble, DMSO: soluble, methanol: soluble

SMILES string

CN1C2CCC1CC(C2)OC(c3ccccc3)c4ccccc4N

InChI

1S/C21H26N2O/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14,22H2,1H3

InChI key

KZFDKINRISJFCO-UHFFFAOYSA-N

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Biochem/physiol Actions

High affinity muscarinic ligand that has been used for affinity purification of muscarinic cholinergic receptors.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
098K4618
038K4624
076K4619
125K4607

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

K Haga et al.
The Journal of biological chemistry, 258(22), 13575-13579 (1983-11-25)
A novel compound, 3-(2'-aminobenzhydryloxy)-tropane (ABT), and an ABT-agarose gel were synthesized and used for the purification of solubilized muscarinic receptors. ABT had a high affinity with an apparent dissociation constant (Kd) of 7 nM for the muscarinic receptors solubilized from
Takafumi Tomida et al.
The Journal of toxicological sciences, 42(5), 641-650 (2017-09-15)
The utility of HepaRG cells as an in vitro cell-based assay system for predicting drug-induced phospholipidosis (PLD) was investigated. In experiment 1, 10 PLD-positive compounds and 11 PLD-negative compounds were selected. HepaRG cells were treated with each compound for 48
Teja Klancic et al.
Biomedicines, 9(1) (2021-01-16)
Pulsed antibiotic treatment (PAT) early in life increases risk of obesity. Prebiotics can reduce fat mass and improve metabolic health. We examined if co-administering prebiotic with PAT reduces obesity risk in rat pups weaned onto a high fat/sucrose diet. Pups
Victor Sebastian-Perez et al.
Journal of enzyme inhibition and medicinal chemistry, 35(1), 511-523 (2020-01-16)
A previous phenotypic screening campaign led to the identification of a quinazoline derivative with promising in vitro activity against Schistosoma mansoni. Follow-up studies of the antischistosomal potential of this candidate are presented here. The in vivo studies in a S. mansoni mouse
A Rinken et al.
Archives of biochemistry and biophysics, 301(1), 158-164 (1993-02-15)
Muscarinic acetylcholine receptors (mAChRs) can be solubilized from porcine atrial membranes in sucrose monolaurate (SM-1200) with retention of up to 80% of N-[3H]methylscopolamine ([3H]NMS) binding activity. The mAChRs solubilized by SM-1200 were relatively stable at 4 degrees C with an
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service