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Merck

C9819

Chondroitin sulfate A sodium salt from bovine trachea

lyophilized powder, BioReagent, suitable for cell culture

Synonym(s):

Alternating Copoly β-glucuronic acid-(1→3)-N-acetyl-β-galactosamine-4-sulfate-(1→4)

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.75
MDL number:

Product Name

Chondroitin sulfate A sodium salt from bovine trachea, lyophilized powder, BioReagent, suitable for cell culture

biological source

bovine trachea

product line

BioReagent

form

lyophilized powder

packaging

poly bottle of 25 g
poly bottle of 5 g

technique(s)

cell culture | mammalian: suitable

surface coverage

20‑2000 μg/cm2

shipped in

ambient

storage temp.

2-8°C

Quality Level

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Application

Chondroitin appears to play a regulatory role for chondrocytes, neural cells, and some tumor cells. Chondroitin sulfate B is used to study ß peptide (1-42) cytotoxicity.

Biochem/physiol Actions

As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.

Disclaimer

Store this product at 2-8°C.

Other Notes

Chondroitin Sulfate A is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetylgalactosamine, D-glucuronic acid, and sulfate residues in equimolar quantities where carbon 4 of the N-acetylgalactosamines is sulfated.

Preparation Note

This product is soluble in water at 100 mg/mL.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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In placental malaria, Plasmodium falciparum-infected erythrocytes adhere to the apical plasma membrane of the placental epithelium, triggering an impairment of placental function detrimental to the fetus. The design of anti-adhesion intervention strategies requires a detailed understanding of the mechanisms involved.
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