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EMU039841

MISSION® esiRNA

targeting mouse Runx1

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGATCCTATCCAGCCTTCCAACTACTGAAGCTGATTTTCAAGGCTACTTAAAAAAAAAAAAACTGCAGCAAACATTAATGGATTTCTGTTGTGTTTAAATTCTCTACAGATTGTATTGTAAATATTTTATGAAGTAGATCATATGTATATATTTATATATACGAGCACATACATTAGTAGCACAATCTTTTAAAGTTACGGCTCTTGCTTTTGAGAAACGAAGTGAGTTTTTCATGGTAAGAGGGGCGCTCTGTATGGAAGACACTCCTAAGTTTTGTATTTTGTTGAGACTCTAAACAAAACTGACCCGCAAGAAAGAAAAACAAACTGACAGGCAACTAACTGGTGGAACTTCCAAATCTAGTTTTTGCTGGTCATTTTTTGGTTGTTGTTGTTGTTCTGCGCATAAATATTTTAGGACGCGTATGGGAATTTTGCTCCGGGACCGTTTGTAATAGCCAAAGACTGAACTTCAACTCTCAAAGCGAGGCTCTGTTGGGCATTTGACTTTGA

Ensembl | mouse accession no.

ENSMUSG00000022952

NCBI accession no.

NM_009821

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... RUNX1(12394), Runx1(12394)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Ken-ichi Takayama et al.
Oncotarget, 6(4), 2263-2276 (2014-12-30)
Androgen receptor (AR) signaling is essential for the development of prostate cancer. Here, we report that runt-related transcription factor (RUNX1) could be a key molecule for the androgen-dependence of prostate cancer. We found RUNX1 is a target of AR and
Gillian Browne et al.
Journal of cellular physiology, 230(10), 2522-2532 (2015-03-25)
Runx1 is a transcription factor essential for definitive hematopoiesis, and genetic abnormalities in Runx1 cause leukemia. Runx1 is functionally promiscuous and acts as either an oncogene or tumor suppressor gene in certain epithelial cancers. Recent evidence suggests that Runx1 is
A de Laurentiis et al.
Oncogene, 34(49), 6018-6028 (2015-04-22)
The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene. Many studies on TEL-AML1 describe specific properties of the fusion protein, but a thorough understanding of its