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Merck

P7700

Protein G–Agarose

lyophilized powder, Contains lactose stabilizers that must be removed prior to use.

Synonym(s):

Protein G resin

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About This Item

UNSPSC Code:
41106500
NACRES:
NA.56
MDL number:
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Product Name

Protein G–Agarose, lyophilized powder, Contains lactose stabilizers that must be removed prior to use.

form

lyophilized powder

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

capacity

≥15 mg/mL binding capacity (human IgG)

storage temp.

−20°C

Quality Level

Application

Protein G-agarose is used in affinity chromatography, protein chromatography, antibody purification and characterization, immunoaffinity matrices, protein A, G and L resins, and purification and detection. Protein G-agarose has been used to study breast cancer and falsely elevated thyroid-stimulating hormone (TSH).

Preparation Note

Prepared with a genetically engineered Protein G which retains its high affinity for IgG and lacks albumin and Fab binding sites and membrane binding regions.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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John Collins et al.
Liver, 22(6), 501-506 (2002-11-26)
Persistent elevation of aspartate aminotransferase (AST) activity in serum due to the presence of a macroenzyme form of AST (macro-AST) may lead to diagnostic confusion in many clinical conditions, particularly those associated with chronic liver disease. We describe a case
Hiroshi Hirai et al.
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Deregulation of cell-cycle control is a hallmark of cancer. Thus, cyclin-dependent kinases (Cdks) are an attractive target for the development of anti-cancer drugs. Here, we report the biological characterization of a highly potent pan-Cdk inhibitor with a macrocycle-quinoxalinone structure. Compound
Ebany J Martinez-Finley et al.
Neurotoxicology and teratology, 33(5), 530-537 (2011-07-26)
Changes within the glucocorticoid receptor (GR) cellular signaling pathway were evaluated in adolescent mice exposed to 50 ppb arsenic during gestation. Previously, we reported increased basal plasma corticosterone levels, decreased hippocampal GR levels and deficits in learning and memory performance
J W Priest et al.
Molecular and biochemical parasitology, 113(1), 117-126 (2001-03-20)
Cryptosporidium parvum is a protozoan parasite of the intestinal epithelium that has caused numerous outbreaks of diarrheal illness in humans. During our studies of the host immune response to C. parvum infection, we noted that two of the immunodominant surface
Susanne Vetterkind et al.
Journal of cellular and molecular medicine, 13(5), 887-895 (2008-05-29)
Par-4 (prostate apoptosis response 4) is a pro-apoptotic protein and tumour suppressor that was originally identified as a gene product up-regulated during apoptosis in prostate cancer cells. Here, we show, for the first time, that Par-4 is expressed and co-localizes

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