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Merck

146358

1-Ethyl-2-pyrrolidone

98%

Synonym(s):

NEP

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About This Item

Empirical Formula (Hill Notation):
C6H11NO
CAS Number:
2687-91-4
Molecular Weight:
113.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24848778
EC Number:
220-250-6
Beilstein/REAXYS Number:
107971
MDL number:
MFCD00003199

Product Name

1-Ethyl-2-pyrrolidone, 98%

InChI key

ZFPGARUNNKGOBB-UHFFFAOYSA-N

InChI

1S/C6H11NO/c1-2-7-5-3-4-6(7)8/h2-5H2,1H3

SMILES string

CCN1CCCC1=O

assay

98%

form

liquid

refractive index

n20/D 1.465 (lit.)

bp

97 °C/20 mmHg (lit.)

density

0.992 g/mL at 25 °C (lit.)

Quality Level

100

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Application

1-Ethyl-2-pyrrolidone was used to modify coir fiber (from Cocos nucifera) by photocuring.

General description

1-Ethyl-2-pyrrolidone is a transdermal absorption-enhancing compound and mechanism of its effect on multilammellar liposome of stratum corneum lipid has been studied.

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
STBL2676
STBK5568
STBK0377
STBJ0978
STBH7138

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Xiaolei Zhu et al.
Aging cell, 16(5), 1073-1082 (2017-08-05)
The accumulation and deposition of beta-amyloid (Aβ) is a key neuropathological hallmark of Alzheimer's disease (AD). Histone deacetylases (HDACs) are promising therapeutic targets for the treatment of AD, while the specific HDAC isoforms associated with cognitive improvement are poorly understood.
Francisco M Pinto et al.
Reproductive biology and endocrinology : RB&E, 8, 104-104 (2010-08-28)
We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neurokinin
Effect of Pretreatment with Ultraviolet Radiation on the Physicomechanical Properties of Photocured Coir (Cocos nucifera) Fiber with 1-Ethyl-2-Pyrrolidone (1-E-2-P) Monomer.
Khan MA, et al.
Polymer-Plastics Technology and Engineering, 45(4), 487-494 (2006)
Ajeet Kaushik et al.
Scientific reports, 7, 45663-45663 (2017-04-05)
In this research, we demonstrate cell uptake of magneto-electric nanoparticles (MENPs) through nanoelectroporation (NEP) using alternating current (ac)-magnetic field stimulation. Uptake of MENPs was confirmed using focused-ion-beam assisted transmission electron microscopy (FIB-TEM) and validated by a numerical simulation model. The
Takeshi Katsuda et al.
Scientific reports, 3, 1197-1197 (2013-02-05)
Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ) in the brain because of an imbalance between Aβ production and clearance. Neprilysin (NEP) is the most important Aβ-degrading enzyme in the brain. Thus, researchers have explored virus-mediated
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