914304
Hyaluronic acid methacrylate
average degree of substitution 35%, average Mw 100,000-150,000 Da
Synonym(s):
Functioanlized hyaluronic, HA methacrylamide, HAMA, Hyaluronic acid MA, Hyaluronic acid (HA) & derivatives
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About This Item
Linear Formula:
(NaC20H28NO15)n
NACRES:
NA.23
UNSPSC Code:
12352106
Form:
(powder or chunk(s) or fibers)
description
NMR: Conforms to structure
Quality Level
form
(powder or chunk(s) or fibers)
mol wt
average Mw 100,000-150,000 Da
color
white to off-white
storage temp.
2-8°C
Application
Hyaluronic acid (HA) is a linear polysaccharide of alternating D-glucuronic acid and N-acetyl-D-glucosamine found primarily in connective tissues. HA based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug deliery applications. The methacrylate functionalized hyaluronic acid is photo-crosslinkable, and can be used to generate crosslinked hydrogels.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Cindy Chung et al.
Tissue engineering. Part A, 15(2), 243-254 (2009-02-06)
Mesenchymal stem cells (MSCs) are multipotent progenitor cells whose plasticity and self-renewal capacity have generated significant interest for applications in tissue engineering. The objective of this study was to investigate MSC chondrogenesis in photo-cross-linked hyaluronic acid (HA) hydrogels. Because HA
Judy Yeh et al.
Biomaterials, 27(31), 5391-5398 (2006-07-11)
Encapsulation of mammalian cells within hydrogels has great utility for a variety of applications ranging from tissue engineering to cell-based assays. In this work, we present a technique to encapsulate live cells in three-dimensional (3D) microscale hydrogels (microgels) of controlled
Bin Duan et al.
Acta biomaterialia, 9(8), 7640-7650 (2013-05-08)
Bioactive and biodegradable hydrogels that mimic the extracellular matrix and regulate valve interstitial cells (VIC) behavior are of great interest as three-dimensional (3-D) model systems for understanding mechanisms of valvular heart disease pathogenesis in vitro and the basis for regenerative