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Merck

922188

Low endotoxin GelMA

bloom 300, Type A, degree of substitution 80%

Synonym(s):

3D Bioprinting, GelMA, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl, Gelatin / GelMA & derivatives

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About This Item

NACRES:
NA.23
UNSPSC Code:
12352202
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Quality Level

form

powder or chunks

impurities

<10 CFU/g Bioburden, <125 EU/g Endotoxin

color

white to off-white

storage temp.

2-8°C

Application

This is a low endotoxin GelMA for use in biomedical research applications.
GelMA can be used to form hydrogels for tissue engineering and 3D bioprinting. Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.

Packaging

500 mg in glass bottle


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Photocrosslinkable gelatin hydrogel for epidermal tissue engineering.
Zhao X, Khademhosseini A
Advanced Helathcare Materials (2015)
Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide
Gupta NV et al.
Indian journal of pharmacy and pharmacology, 69(1, 64-68 (2007)
Kristel W M Boere et al.
Acta biomaterialia, 10(6), 2602-2611 (2014-03-05)
Hydrogels can provide a suitable environment for tissue formation by embedded cells, which makes them suitable for applications in regenerative medicine. However, hydrogels possess only limited mechanical strength, and must therefore be reinforced for applications in load-bearing conditions. In most