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271012

N,N-Dimethylacetamide

anhydrous, 99.8%

Synonym(s):

DMAc

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About This Item

Linear Formula:
CH3CON(CH3)2
CAS Number:
127-19-5
Molecular Weight:
87.12
UNSPSC Code:
12352111
NACRES:
NA.21
PubChem Substance ID:
57648218
EC Number:
204-826-4
Beilstein/REAXYS Number:
1737614
MDL number:
MFCD00008686
Assay:
99.8%
Grade:
anhydrous
Bp:
164.5-166 °C (lit.)
Vapor pressure:
2 mmHg ( 25 °C), 4 mmHg ( 38 °C)
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grade

anhydrous

Quality Level

300

vapor density

3 (vs air)

vapor pressure

2 mmHg ( 25 °C), 4 mmHg ( 38 °C)

assay

99.8%

form

liquid

autoignition temp.

914 °F

expl. lim.

1.8 %, 100 °F, 11.5 %, 160 °F

impurities

<0.005% water

evapn. residue

<0.001%

refractive index

n20/D 1.437 (lit.)

pH

4 (20 °C, 200 g/L)

bp

164.5-166 °C (lit.)

mp

−20 °C (lit.)

density

0.937 g/mL at 25 °C (lit.)

SMILES string

CN(C)C(C)=O

InChI

1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

InChI key

FXHOOIRPVKKKFG-UHFFFAOYSA-N

Application

N,N-Dimethylacetamide may be used as a solvent in the following processes:
  • Palladium (II) acetate-butyldi-1-adamantylphosphine catalyzed arylation of 2-isobutylthiazole with chlorobenzene to form 5-phenyl-2-isobutylthiazole.
  • Synthesis of β-, γ-, and δ-metallo ester intermediates that can react with acid chlorides to form γ-, δ-, and ε-keto esters.
  • Synthesis of (R)-(-)-methyl 1,1′-binaphthyl-2,2′-diylphosphate that can be used as a precursor for preparing (R)-(+)-1,1′-binaphthalene-2,2′-diol.

Packaging

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Other Notes

The article number 271012-4X2L will be discontinued. Please order the single bottle 271012-2L which is physically identical with the same exact specifications.

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

127-19-5

CAS No.

127-19-5

CAS No.

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT4786
SHBT2432
SHBS9128
SHBS4461
SHBR8797

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Ethyl 5-oxo-6-methyl-6-heptenoate from methacryloyl chloride and ethyl 4-iodobutyrate
Yoshinao T, et al
Organic Syntheses, 67, 98-98 (1989)
Density and Viscosity Measurements for Binary Mixtures of 1-Ethyl-3-methylimidazolium Tetrafluoroborate ([Emim][BF4]) with Dimethylacetamide, Dimethylformamide, and Dimethyl Sulfoxide.
Fan XH, et al.
Journal of Chemical and Engineering Data (2016)
(R)-(+)-1,1'-Binaphthalene-2,2'-diol
Truesdale LK
Organic Syntheses, 67, 13-13 (1989)
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