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Merck

B1385

Butoxamine hydrochloride

analytical standard, for drug analysis, mixture of diastereomers

Synonym(s):

α-(1-[t-Butylamino]ethyl)-2,5-dimethoxybenzyl alcohol

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About This Item

Empirical Formula (Hill Notation):
C15H25NO3 · HCl
CAS Number:
Molecular Weight:
303.82
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
227-169-5
MDL number:
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Product Name

Butoxamine hydrochloride, analytical standard, for drug analysis, mixture of diastereomers

Quality Level

InChI key

URPAECSKKQLCII-UHFFFAOYSA-N

InChI

1S/C15H25NO3.ClH/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6;/h7-10,14,16-17H,1-6H3;1H

SMILES string

Cl.COc1ccc(OC)c(c1)C(O)C(C)NC(C)(C)C

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Butoxamine hydrochloride is a β-andrenoceptor antagonist, which shows β2-selectivity.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Claudio Molinari et al.
Endocrinology, 148(8), 4080-4090 (2007-04-28)
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Adrenaline quickly inhibits the release of histamine from mast cells. Besides β2-adrenergic receptors, several in vitro studies also indicate the involvement of α-adrenergic receptors in the process of exocytosis. Since exocytosis in mast cells can be detected electrophysiologically by the
Elena Grossini et al.
Endocrinology, 148(2), 806-812 (2006-11-18)
The peptide ghrelin has been linked to the atherosclerotic process and coronary artery disease. We planned to study, for the first time, the primary effects of ghrelin on the intact coronary circulation and determine the mechanisms involved. In 24 sodium
Jiayin Lu et al.
International journal of molecular sciences, 22(3) (2021-02-06)
Restraint stress causes various maternal diseases during pregnancy. β2-Adrenergic receptor (β2-AR) and Forkhead transcription factor class O 1 (FOXO1) are critical factors not only in stress, but also in reproduction. However, the role of FOXO1 in restraint stress, causing changes
Cardiovascular teratogenicity of terbutaline and ritodrine in the chick embryo
Lenselink R.D, et al.
American Journal of Obstetrics and Gynecology, 171(2), 501-506 (1994)

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