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C3025

(±)-Chlorpheniramine maleate salt

Name: (±)-Chlorpheniramine maleate salt
Brand: SIGMA

≥99% (perchloric acid titration)

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₉ClN₂ · C₄H₄O₄

CAS Number:

113-92-8

Molecular Weight:

390.86

NACRES:

NA.77

PubChem Substance ID:

24277767

UNSPSC Code:

12352116

EC Number:

204-037-5

MDL number:

MFCD00069225

Assay:

≥99% (perchloric acid titration)

Form:

powder

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Properties

Quality Segment

100

assay

≥99% (perchloric acid titration)

form

powder

mp

130-135 °C (lit.)

originator

Bayer

SMILES string

CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O

InChI

1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

DBAKFASWICGISY-BTJKTKAUSA-N

Gene Information

human ... HRH1(3269)

Description

General description

Chlorpheniramine maleate (CPM)/(3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine is an alkylamine antihistamine.

Application

(±)-Chlorpheniramine maleate salt has been used:

as H1 receptor antagonist to determine the receptor function
to block the effect of compound 48/80 on plasma IGF-I
as a standard for fast sensing and determination by sequential injector coupled with potentiometer

Biochem/physiol Actions

H₁ Histamine receptor antagonist.

Chlorpheniramine maleate (CPM) can prevent rhinitis and urticaria. It is used to cure several allergic conditions. This antihistamine is used in small-animal veterinary practices.