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Merck

320056

1,10-Phenanthroline monohydrate

redox indicator, ACS reagent, 99%

Synonym(s):

o-Phenanthroline monohydrate

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About This Item

Empirical Formula (Hill Notation):
C12H8N2 · H2O
CAS Number:
Molecular Weight:
198.22
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-629-2
MDL number:
Beilstein/REAXYS Number:
4008096
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Product Name

1,10-Phenanthroline monohydrate, ACS reagent, 99%

grade

ACS reagent

Quality Level

assay

99%

technique(s)

titration: suitable

mp

100-104 °C (lit.)

suitability

passes test for determination of iron, passes test for redox indicator

SMILES string

O.c1cnc2c(c1)ccc3cccnc23

InChI

1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2

InChI key

PPQJCISYYXZCAE-UHFFFAOYSA-N

Gene Information

human ... FNTA(2339)

Application

1,10-Phenanthroline monohydrate is an aromatic nitrogen heterocycle that may be used as a chelating agent in the preparation of metal-chelate complexes.
When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.

Biochem/physiol Actions

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.


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pictograms

Skull and crossbonesEnvironment

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt (III) and iron (II) with 1, 10-phenanthroline and 2, 2'-bipyridine.
Carter MT, et al.
Journal of the American Chemical Society, 111(24), 8901-8911 (1989)
Photophysics and photochemistry of aromatic nitrogen heterocycles. Fluorescence from 2, 2'-bipyridine and 1, 10-phenanthroline.
Henry MS & Hoffman MZ.
The Journal of Physical Chemistry, 83(5), 618-625 (1979)
Bhumi Parikh et al.
Journal of food science and technology, 55(4), 1499-1507 (2018-04-03)
Pulses are valued for their protein content and are good source of bioactive phytochemicals. The objectives of this study were to estimate total phenolic content (TPC), flavonoid content and total antioxidant capacity (TAC) through six different assay methods from twenty