C5024
Carbonic Anhydrase from bovine erythrocytes
non-denaturing PAGE marker
Synonym(s):
Carbonate Dehydratase, Carbonate Hydrolyase
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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-576-6
MDL number:
Quality Level
form
lyophilized powder
mol wt
~29 kDa
suitability
suitable for marker for electrophoresis (non-denaturing PAGE)
storage temp.
−20°C
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Application
This product is used as a marker to determine the molecular mass of an unknown protein in non-denaturing electrophoresis systems. In such systems, proteins often retain their biological activity, thus allowing in-gel detection using specific substrate stains. This technique also facilitates the recovery of the active protein. The product yields 3 bands.
Preparation Note
0.9-1.4 mg/mL after reconstitution with 1 mL of water
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Yuzhu Bian et al.
Artificial cells, nanomedicine, and biotechnology, 41(1), 60-68 (2013-01-26)
Even though erythrocytes transport both oxygen and carbon dioxide, research on blood substitutes has concentrated on the transport of oxygen and its vasoactivity and oxidative effects. Recent study in a hemorrhagic shock animal model shows that the degree of tissue
A O Kaya et al.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 17(4), 663-668 (2013-01-22)
Hypoxia is common in many solid tumors such as breast, head-neck, and soft tissue malignancies. Hypoxia causes overexpression of hypoxia inducible factor-1 alpha (HIF-1α) and carbonic anhydrase IX (CA IX) which are associated with unfavorable prognosis in breast cancer. In
Barend Andre Stander et al.
PloS one, 7(12), e52205-e52205 (2013-01-10)
Antimitotic compounds are still one of the most widely used chemotherapeutic anticancer drugs in the clinic today. Given their effectiveness against cancer it is beneficial to continue enhancing these drugs. One way is to improve the bioavailability and efficacy by
Tristan J Horner et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(7), 2500-2505 (2013-01-31)
The global marine distributions of Cd and phosphate are closely correlated, which has led to Cd being considered as a marine micronutrient, despite its toxicity to life. The explanation for this nutrient-like behavior is unknown because there is only one
Nadia Lounnas et al.
Cancer letters, 333(1), 76-88 (2013-01-26)
The membrane-bound carbonic anhydrase isoforms CAIX and CAXII, underpin a pH-regulating system that enables hypoxic tumor cell survival. Here, we observed for the first time an upregulation of CAXII in T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LL) cells. First we showed that
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