T9250
Thymidine
≥99%, synthetic (organic), powder
Synonym(s):
1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, 1-(2-Deoxy-β-D-ribofuranosyl)thymine, 2′-Deoxythymidine, Thymine deoxyriboside, dT
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About This Item
Empirical Formula (Hill Notation):
C10H14N2O5
CAS Number:
Molecular Weight:
242.23
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-070-4
MDL number:
Beilstein/REAXYS Number:
89285
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear, colorless
Product Name
Thymidine, ≥99%
biological source
synthetic (organic)
Quality Level
assay
≥99%
form
powder
mp
186-188 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless
SMILES string
CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
InChI
1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChI key
IQFYYKKMVGJFEH-XLPZGREQSA-N
Gene Information
human ... DTYMK(1841)
General description
Thymidine is also referred to as pyrimidine deoxynucleoside. Deoxythymidine is a nucleoside present in DNA. In a DNA double stranded structure, thymidine pairs with deoxyadeninosine. It is useful in cell synchronization during S-phase. In the salvage pathway of pyrimidines, pyrimidine phosphorylase reversibly converts thymine to thymidine.
Application
Thymidine has been used:
- as a supplement in HL5-modified medium for cell culture
- to incubate cells in cell-cycle analysis
- in cell synchronization
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Stangel D, et al.
The Journal of Surgical Research, 197(1), 91-100 (2015)
Molecular Biology, Principles of Genome Function: Biology, Molecular biology (2016)
Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase
Lee KJ, et al.
Nucleic Acids Research, 44(4), 1732-1745 (2015)