A5955

Antibiotic Antimycotic Solution (100×), Stabilized

Name: Antibiotic Antimycotic Solution (100×), Stabilized
Brand: SIGMA

suspension, suitable for cell culture, BioReagent

Synonym(s):

Penicillin-Streptomycin-Amphotericin B Suspension

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About This Item

UNSPSC Code:

12352207

NACRES:

NA.76

MDL number:

MFCD00130520

Product Name

Antibiotic Antimycotic Solution (100×), Stabilized, with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture

sterility

0.1 μm filtered

product line

BioReagent

form

suspension

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

yellow

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
fungi
yeast

application(s)

agriculture

mode of action

cell wall synthesis | interferes

shipped in

dry ice

storage temp.

−20°C

Quality Level

200

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Related Categories

Antibiotics

Biochemicals

Cell Culture Supplements & Reagents

Application

Antibiotic antimycotic solution has been used:

as a supplement in different types of cell culture media.
as a component of phosphate buffer saline (PBS) sterile solution to prevent contamination of periodontal ligament fibroblasts (PDLF) tissues that are isolated and cultured in the experiments.
as a component of storage solution for preserving tracheal segments harvested for subsequent experimental investigation.

Biochem/physiol Actions

Mode of Action: Penicillin acts by inhibiting bacterial cell-wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome and causes miscoding. Amphotericin B interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.

Antimicrobial spectrum: Includes Gram-negative bacteria, Gram-positive bacteria, fungi and yeasts.

General description

Antibiotic Antimycotic Solution is formulated to contain 10,000 units penicillin, 10 mg streptomycin and 25μg Amphotericin B per mL, and is solubilized in a proprietary citrate buffer. It is recommended for use in cell culture applications at 10mL/L. Antibioticantimycotic solution is generally used to prevent the growth of harmful microorganisms including bacteria and fungi in cell culture media.

pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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