SCP0121
[Des-Cys1]-Calcitonin, salmon
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About This Item
Empirical Formula (Hill Notation):
C142H237N43O47S1
Molecular Weight:
3330.73
NACRES:
NA.32
UNSPSC Code:
12352209
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Application
Calcitonin, a 32 amino acid polypeptide, is involved in the regulation of calcium and phosphorous metabolism often antagonistic to parathyroid hormone (PTH). [Des-Cys1]-Calcitonin, salmon (Des-Cys1-sCT) has the N-terminal cysteine residue removed.
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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J H Feyen et al.
Biochemical and biophysical research communications, 187(1), 8-13 (1992-08-31)
Structural requirements for binding to the bone calcitonin (CT) receptor and for CT bioactivity both in vitro and in vivo were assessed for a series of N-terminally truncated, N alpha-acetylated, fragments of salmon calcitonin (sCT). Sequential deletion of amino acid
K Uda et al.
Biological & pharmaceutical bulletin, 22(3), 244-252 (1999-04-29)
Various derivatives of human calcitonin have been synthesized and their biological characteristics compared with those of existing calcitonins. The acute effects of these analogues in reducing serum calcium levels and suppressing appetite were assessed in rats. A calcitonin analogue, PO-1
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