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SML4062

Sulfo-NHS-SS-Biotin

>80% Na basis (elemental analysis)

Synonym(s):

3-[[2-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-propanoic acid 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester sodium salt, 1-[3-[[2-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]-1-oxopropoxy]-2,5-dioxo-3-pyrrolidinesulfonic acid monosodium salt, Sulfo-NHS-SS-Biotin sodium, Biotin-SS-Sulfo-Osu, EZ-Link Sulfo-NHS-SS-Biotin

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About This Item

Empirical Formula (Hill Notation):
C19H28N4NaO9S4
CAS Number:
325143-98-4
Molecular Weight:
607.70
NACRES:
NA.21
Assay:
>80% Na basis (elemental analysis)
Form:
powder
Storage condition:
desiccated
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Quality Segment

100

assay

>80% Na basis (elemental analysis)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

O=C(C(CC1=O)S(=O)(O[Na])=O)N1OC(CCSSCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O

Biochem/physiol Actions

Sulfo-NHS-SS-biotin facilitates targeted and reversible protein biotinylation, serving diverse experimental and analytical objectives.
Sulfo-NHS-SS-biotin, a cleavable and water-soluble trifunctional derivatization agent that cannot enter cells, is utilized for labeling primary amines. This enables subsequent purification and enrichment through streptavidin-coated beads, followed by the release of thiolated primary amides under conditions that break disulfide bonds. Sulfo-NHS-SS-biotin finds applications in protein purification, reversible labeling, identifying target proteins, quantification of cell-surface proteins and conducting affinity-based assays.

Disclaimer

Hygroscopic

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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