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Merck

269913

3-(Trimethylsilyl)propionic-2,2,3,3-d4 acid sodium salt

98 atom % D

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About This Item

Linear Formula:
(CH3)3SiCD2CD2CO2Na
CAS Number:
Molecular Weight:
172.27
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
EC Number:
246-286-2
Beilstein/REAXYS Number:
4046239
MDL number:
Assay:
≥98.0% (NMR)
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isotopic purity

98 atom % D

Quality Level

assay

≥98.0% (NMR)

impurities

≤0.5% water (Karl Fischer)

pH

7.0-9.0 (1% in solution)

mass shift

M+4

SMILES string

[Na+].[2H]C([2H])(C([O-])=O)C([2H])([2H])[Si](C)(C)C

InChI

1S/C6H14O2Si.Na/c1-9(2,3)5-4-6(7)8;/h4-5H2,1-3H3,(H,7,8);/q;+1/p-1/i4D2,5D2;

InChI key

OIIWPAYIXDCDNL-HGFPCDIYSA-M

Application


  • Rapid separation and quantitation of curcuminoids combining pseudo two-dimensional liquid flash chromatography and NMR spectroscopy: This research demonstrates the application of 3-(Trimethylsilyl)propionic-2,2,3,3-d₄ acid sodium salt in the field of NMR spectroscopy, particularly emphasizing its role as an internal standard in the quantification of curcuminoids. The study showcases a novel method that combines pseudo two-dimensional liquid flash chromatography with NMR spectroscopy, providing a faster, more accurate analytical approach. This method significantly enhances the efficiency and reliability of chemical analysis in pharmaceutical and biomedical research, making it a valuable technique for analytical chemists in academia (Jayaprakasha et al., 2013).




Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Sung Ha Ryu et al.
The Journal of toxicological sciences, 44(1), 57-71 (2019-01-11)
Cisplatin (CP) is an anti-cancer drug used for treatment of solid tumors, but the major adverse effect is drug-induced nephrotoxicity. The current study aimed to determine biomarkers that might predict nephrotoxicity induced by CP using serum or urinary proton nuclear
Raghunath Pariyani et al.
Journal of food science, 85(2), 364-373 (2020-01-25)
Sea buckthorn (Hippophaë rhamnoides) is increasingly cultivated to produce raw materials for food and nutraceuticals. There is little knowledge on composition of sea buckthorn leaves (SBLs) and the key factors influencing the composition. This research aims to unravel the metabolic
Simon Deusch et al.
Frontiers in microbiology, 8, 1605-1605 (2017-09-09)
The structure and function of the microbiome inhabiting the rumen are, amongst other factors, mainly shaped by the animal's feed intake. Describing the influence of different diets on the inherent community arrangement and associated metabolic activities of the most active