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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... FGF7(2252)
Input:
sample type cell culture supernatant(s)
sample type plasma
sample type urine
sample type serum
sample type plasma
sample type urine
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type plasma
sample type urine
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.5 pg/mL
standard curve range: 0.55-400 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FGF7(2252)
General description
The gene FGF7 (fibroblast growth factor 7) is mapped to human chromosome 15q21.1. The encoded protein belongs to the fibroblast growth factor family and is secreted by mesenchymal cells.
The Human FGF-7 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human FGF-7 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human FGF7
Application
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
FGF7 (fibroblast growth factor 7) is involved in the development of skin and sweat glands, wound healing and cutaneous homeostasis. It controls keratinocyte differentiation and viability by modulating autophagy. FGF7 also participates in embryonic development, tumorigenesis, cell proliferation, migration and differentiation. It is linked with several disorders like nonsyndromic cleft lip and palate, thyroid volume, goiter risk and chronic obstructive pulmonary disease. FGF7 plays an important role in the morphology of developing lungs. Absence of the FGF7 activity decreases airway branching during development. During injury, it is involved in airway repair.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
10 - Combustible liquids
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Related Content
Instructions
Oncogenic mutations of ALK kinase in neuroblastoma
Chen Y, et al.
Nature, 455(7215), 971-974 (2008)
Association between fibroblast growth factor 7 and the risk of chronic obstructive pulmonary disease
Xu SC, et al.
Acta Pharmacologica Sinica, 33(8), 998-1003 (2012)
Recombinant keratinocyte growth factor 1 in tobacco potentially promotes wound healing in diabetic rats
Feng ZG, et al.
BioMed Research International (2014)
