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Merck

1.09336

LiChroprep® Si 60 (15-25 µm)

for liquid chromatography

Synonym(s):

Silica, Silicon dioxide

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About This Item

Linear Formula:
SiO2
CAS Number:
Molecular Weight:
60.08
UNSPSC Code:
41115711
EC Index Number:
231-545-4
MDL number:
Technical Service
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material

silica gel (irregularly-shaped)

Quality Level

product line

LiChroPrep®

potency

>5000 mg/kg LD50, skin (Rabbit)

matrix active group

Irregular-Shaped Silica Gel

particle size

15-40 μm

pore size

6 nm mean pore size

pH

7 (20 °C, 100 g/L in H2O, slurry)

bp

2230 °C (lit.)

mp

>1600 °C (lit.)

bulk density

200‑800 kg/m3

application(s)

pharma/biopharma processes
plasma purification

separation technique

reversed phase

storage temp.

no temp limit

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

General description

Irregular-shaped Silica gel with narrow, well defined particle size distribution delivering high separating performance, permeability and good reproducibility

Application

LiChroprep Si 60 (15-25 µm) for liquid chromatography. CAS 7631-86-9, EC Number 231-545-4, chemical formula SiO₂.

Features and Benefits

LiChroprep® Si 60 (15-25 µm) provides users with:

  • Reproducible, homogeneous, irregularly shaped silica gel matrix
  • Narrow, well defined particle size distribution for high performance and high permeability
  • Large batch sizes up to 200 kg in the modification

Packaging

Plastic bottle

Analysis Note

pH-value (10 % suspension): 6.5 - 7.5
Loss on drying (150 °C): 5.5 - 6.5 %
Specific surface area (according to BET): 480 - 540 m²/g
Pore volume (N₂-isotherm): 0.74 - 0.84 ml/g
particle size (Malvern) (d10): 11.0 - 16.0 µm
particle size (Malvern) (d50): 18.0 - 24.0 µm
particle size (Malvern) (d90): 27.0 - 37.0 µm
Application test (2-Nitrotoluene): conforms
Pressure: ≤ 15.0 bar
Separation efficiency (2-Nitrotoluene): ≥ 8000
Leading: ≤ 7 %
Tailing: ≤ 11 %
Symmetry: 0.8 - 1.5
Capacity factor: ≥ 0.3
The specific surface is related to silica gel raw material.

Legal Information

LICHROPREP is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

13 - Non Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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