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About This Item
Linear Formula:
C2H5CH(COOH)2
CAS Number:
Molecular Weight:
132.11
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
210-007-2
Beilstein/REAXYS Number:
774334
MDL number:
Product Name
Ethylmalonic acid, 97%
InChI key
UKFXDFUAPNAMPJ-UHFFFAOYSA-N
InChI
1S/C5H8O4/c1-2-3(4(6)7)5(8)9/h3H,2H2,1H3,(H,6,7)(H,8,9)
SMILES string
CCC(C(O)=O)C(O)=O
assay
97%
form
solid
mp
112-114 °C (lit.)
Quality Level
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Related Categories
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Imad Dweikat et al.
Metabolic brain disease, 27(4), 613-616 (2012-05-16)
Ethylmalonic encephalopathy (EE) is a rare autosomal recessive disorder caused by mutations in the ETHE1 gene and characterized by chronic diarrhea, encephalopathy, relapsing petechiae and acrocyanosis. Nephrotic syndrome has been described in an infant with EE but the renal histology
Bianca T van Maldegem et al.
Pediatric research, 67(3), 304-308 (2009-12-03)
Short-chain acyl-CoA dehydrogenase deficiency (SCADD) is an inborn error, biochemically characterized by increased plasma butyrylcarnitine (C4-C) concentration and increased ethylmalonic acid (EMA) excretion and caused by rare mutations and/or common gene variants in the SCAD encoding gene. Although its clinical
Patrícia Fernanda Schuck et al.
Behavioural brain research, 197(2), 364-370 (2008-10-28)
High concentrations of ethylmalonic acid (EMA) are found in tissues and biological fluids of patients affected by ethylmalonic encephalopathy (EE), as well as by deficiency of short-chain acyl-CoA dehydrogenase (SCAD) activity and other illnesses characterized by developmental delay and other
Lindsay Tomlinson et al.
Toxicological sciences : an official journal of the Society of Toxicology, 129(2), 268-279 (2012-07-24)
Ibipinabant (IBI), a potent cannabinoid-1 receptor (CB1R) antagonist, previously in development for the treatment of obesity, causes skeletal and cardiac myopathy in beagle dogs. This toxicity was characterized by increases in muscle-derived enzyme activity in serum and microscopic striated muscle
Raffaella Zannolli et al.
NMR in biomedicine, 23(4), 353-358 (2010-02-27)
Our aim was to compare urinary ethylmalonic acid (EMA) levels in subjects who had no apparent clinical reason to have increased levels of this substance but were suffering from non-specific CNS impairment, and healthy controls. Urinary EMA concentrations detected by
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