328014
3-Methylhippuric acid
98%
Synonym(s):
N-(3-Methylbenzoyl)glycine, m-Toluric acid
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
CH3C6H4CONHCH2CO2H
CAS Number:
Molecular Weight:
193.20
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
InChI
1S/C10H11NO3/c1-7-3-2-4-8(5-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13)
SMILES string
Cc1cccc(c1)C(=O)NCC(O)=O
InChI key
YKAKNMHEIJUKEX-UHFFFAOYSA-N
assay
98%
mp
138-140 °C (lit.)
functional group
amide, carboxylic acid
Quality Level
Related Categories
General description
3-Methylhippuric acid is also referred as m-methyl-hippuric acid. It is major product of xylene biotransformation in urine.
Application
3-Methylhippuric acid was employed as biological marker in studies on occupational exposure to xylene (solvent).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
R Tardif et al.
Occupational and environmental medicine, 51(3), 187-191 (1994-03-01)
This study was undertaken to determine whether previous subacute treatment with ethanol could modify the kinetics of m-xylene in humans. A group of six volunteers was exposed twice to either 100 or 400 ppm of m-xylene during two hours (between
D de Carvalho et al.
International archives of occupational and environmental health, 63(1), 33-37 (1991-01-01)
The industrial solvents, toluene and xylene, have physicochemical properties that can be hazardous to the workers exposed. Since hippuric acid and m-methyl-hippuric acid represent the products of toluene and xylene biotransformation in urine, they are used as biological markers in
M Ogata et al.
International archives of occupational and environmental health, 61(1-2), 131-140 (1988-01-01)
An attempt was made to establish a method for the direct determination of urinary concentrations of creatinine, hippuric acid, methylhippuric acid and mandelic acid by automated high performance liquid chromatography (HPLC). Urine was diluted with distilled water or mobile phase
Determination of methylhippuric acid in human urine by high-performance liquid chromatography and by isotachophoresis.
J Sollenberg et al.
Journal of chromatography, 343(2), 419-423 (1985-10-11)
Possible preferential metabolism of xylene isomers following occupational exposure to mixed xylenes.
M J Miller et al.
International archives of occupational and environmental health, 72(2), 89-97 (1999-04-10)
Solvent exposures commonly involve mixtures of substances or mixtures of isomers of a single solvent. These may be metabolised through common pathways, resulting in the potential for metabolic interactions. These may then lead to accumulation of solvent or metabolic intermediates
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service