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Merck

810156C

Avanti

18:1-12:0 NBD PE

Avanti Research - A Croda Brand

Synonym(s):

1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C41H70N5O11P
CAS Number:
Molecular Weight:
840.00
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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Product Name

18:1-12:0 NBD PE, Avanti Research - A Croda Brand 810156C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810156C-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810156C

concentration

1 mg/mL (810156C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is localized at the membrane interface. Fluorescent NBD label is covalently linked to the headgroup of phosphatidylethanolamine. Phosphoethanolamine is mostly present in brain and is the second most abundant, metabolically related aminophospholipid.

Application

18:1-06:0 NBD PE may be used as a component of liposome in cross-linking experiment and to determine M13 coat protein selectivity toward phospholipids headgroups.

Biochem/physiol Actions

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a key role as a fluorescent analog in the studies of organization and dynamics of membranes. NBD PE contributes in monitoring Red edge excitation shift (REES) effects with the unique motional and dielectric properties it possesses.

Packaging

5 mL Amber Glass Screw Cap Vial (810156C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash



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Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et Biophysica Acta, 1861(6), 1152-1161 (2019)
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
Fernandes F, et al.
Biophysical Journal, 282(52), 37298-37302 (2007)
Fluorescent methods to study biological membranes, 37-50 (2012)