ABN262
Anti-Trypsin-3 Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Trypsin-3, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
immunohistochemistry: suitable (paraffin), western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PRSS3(5646)
General description
Trypsin-3 is also called Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, and Trypsin IV and belongs to the peptidase S1 family. Trypsin-3 is a digestive protease that specifically degrades trypsin inhibitors and may be involved in the processing of defensins, including DEFA5, in the ileum. Trypsin-3 is expressed in pancreas, brain and in Paneth cells, at the base of small intestinal crypts.
~26 kDa observed. Four isoforms are known to exist due to alternative splicing.
Immunogen
KLH-conjugated linear peptide corresponding to the human Trypsin-3.
Application
Anti-Trypsin-3 Antibody is a highly specific rabbit polyclonal antibody, that targets Trypsin & has been tested in western blotting & IHC (Paraffin).
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Trypsin-3 in human pancreatic, cerebellum, and thalamus tissues.
Biochem/physiol Actions
Other homologies: Rat (82% sequence homology), Mouse (72% sequence homology).
Analysis Note
Evaluated by Western Blotting in human pancreas tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected Trypsin-3 in 10 µg of human pancreas tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected Trypsin-3 in 10 µg of human pancreas tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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