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About This Item
Empirical Formula (Hill Notation):
C10H8N2S2
CAS Number:
Molecular Weight:
220.31
UNSPSC Code:
12352112
NACRES:
NA.25
PubChem Substance ID:
EC Number:
218-343-1
Beilstein/REAXYS Number:
154629
MDL number:
Product Name
2,2′-Dithiodipyridine, ≥99.0% (GC)
InChI key
HAXFWIACAGNFHA-UHFFFAOYSA-N
InChI
1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H
SMILES string
S(Sc1ccccn1)c2ccccn2
assay
≥99.0% (GC)
form
solid
mp
56-58 °C (lit.)
57-59 °C
storage temp.
2-8°C
Quality Level
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Other Notes
For the determination of sulfhydryl groups in biological materials
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Determination of sulfhydryl groups with 2,2'- or 4,4'-dithiodipyridine.
D R Grassetti et al.
Archives of biochemistry and biophysics, 119(1), 41-49 (1967-03-01)
Kazuhiko Mochida et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 149(4), 624-630 (2009-02-13)
In a previous study, we demonstrated that exposure to an antifouling biocide, copper pyrithione (CuPT), early during life induced vertebral deformity in the larvae of a marine fish, the mummichog (Fundulus heteroclitus). Skeletal deformities may be caused by inhibition by
Mark L Dallas et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 25(5), 1519-1530 (2011-01-21)
Oxidative stress induces neuronal apoptosis and is implicated in cerebral ischemia, head trauma, and age-related neurodegenerative diseases. An early step in this process is the loss of intracellular K(+) via K(+) channels, and evidence indicates that K(v)2.1 is of particular
Karlhans F Che et al.
European journal of immunology, 40(8), 2248-2258 (2010-05-11)
Priming of T cells in lymphoid tissues of HIV-infected individuals occurs in the presence of HIV-1. DC in this milieu activate T cells and disseminate HIV-1 to newly activated T cells, the outcome of which may have serious implications in
Zita Hertelendi et al.
Antioxidants & redox signaling, 10(7), 1175-1184 (2008-03-12)
This study sought to characterize the relation between the oxidation of protein sulfhydryl (SH) groups and Ca2+-activated force production in the human myocardium. Triton-permeabilized left ventricular cardiomyocytes from donor hearts were exposed to an oxidative (2,2'-dithiodipyridine, DTDP) agent in vitro
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