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Merck

13447

Sodium nitrite

puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E 250, 99-100.5% (calc. to the dried substance)

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About This Item

Linear Formula:
NaNO2
CAS Number:
7632-00-0
Molecular Weight:
69.00
UNSPSC Code:
12352302
PubChem Substance ID:
329750180
EC Number:
231-555-9
MDL number:
MFCD00011118
Assay:
99-100.5% (calc. to the dried substance)
Form:
solid

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Product Name

Sodium nitrite, puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E 250, 99-100.5% (calc. to the dried substance)

InChI key

LPXPTNMVRIOKMN-UHFFFAOYSA-M

InChI

1S/HNO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1

SMILES string

[Na+].[O-]N=O

grade

puriss.

assay

99-100.5% (calc. to the dried substance)

form

solid

autoignition temp.

914 °F

quality

meets analytical specification of Ph. Eur., BP, USP, FCC, E 250

impurities

acidity or alcalinity, in accordance
 residual solvents, complies
≤0.001% heavy metals (as Pb)

loss

≤0.2% loss on drying, 4 h (on silica gel)
≤0.25% loss on drying (on vacuum)

mp

271 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

As: ≤2 mg/kg
Ca: ≤50 mg/kg
Hg: ≤1 mg/kg
Pb: ≤4 mg/kg

suitability

complies for appearance of solution

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Application

Sodium nitrite has been used for the quantitative determination of nitrite in culture medium. It may be used in the preparation of isopropyl nitrite, via reaction with isope alcohol.

General description

Combined effect of NaNO2 and NaCl on the growth of Listeria monocytogenes in tryptone soya broth has been evaluated using automated turbidimetric system. Its carcinogenic effects have been examined in F-344 rats.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Ox. Sol. 3

Storage Class

5.1B - Oxidizing hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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A Maekawa et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 20(1), 25-33 (1982-02-01)
The carcinogenicity of sodium and of sodium nitrate was examined in F-344 rats. Sodium nitrite was administered in the drinking-water for 2 yr at levels of 0.125 or 0.25%. Sodium nitrate was given in the diet at levels 2.5 or
Oscar Zannou et al.
Molecules (Basel, Switzerland), 25(16) (2020-08-23)
Deep eutectic solvents (DESs) have got huge interest as new green and sustainable solvents for the extraction of bioactive compounds from plants in recent decades. In the present study, we aimed to investigate the effectiveness of hydrophilic DES for the
Eagleson M.
Concise Encyclopedia Chemistry, 556-556 (1994)
P J McClure et al.
International journal of food microbiology, 14(1), 77-91 (1991-10-01)
An automated turbidimetric system using multiwelled plates was used to examine the effects of different combinations of NaCl (0.5-8.0% w/v), NaNO2 (0-400 micrograms/ml) pH (4.6-7.4) and temperature (5-30 degrees C) on the growth of Listeria monocytogenes in tryptone soya broth.
R Kokkola et al.
Scandinavian journal of immunology, 61(1), 1-9 (2005-01-13)
Abstract High-mobility group box chromosomal protein 1 (HMGB1) is a protein with both intranuclear functions and extracellular cytokine-like effects. In this report, we study possible candidate receptors for HMGB1 on macrophages (Mphi) and define pathways activated by HMGB1 binding. Bone
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