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Merck

63535

Manganese(II) chloride tetrahydrate

BioUltra, Molecular Biology, ≥99.0% (KT)

Synonym(s):

Manganese chloride tetrahydrate, Manganese dichloride tetrahydrate, MnCl2.4H2O

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About This Item

Linear Formula:
MnCl2 · 4H2O
CAS Number:
13446-34-9
Molecular Weight:
197.91
EC Number:
231-869-6
MDL number:
MFCD00149792
NACRES:
NA.25
PubChem Substance ID:
57651943
UNSPSC Code:
12352302
assay:
≥99.0% (KT)
grade:
Molecular Biology
solubility:
H2O: 0.5 M at 20 °C, clear, colorless

Product Name

Manganese(II) chloride tetrahydrate, BioUltra, Molecular Biology, ≥99.0% (KT)

InChI key

CNFDGXZLMLFIJV-UHFFFAOYSA-L

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2

SMILES string

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

grade

Molecular Biology

product line

BioUltra

assay

≥99.0% (KT)

impurities

DNases, none detected
 RNases, none detected
 insoluble matter, passes filter test
 phosphatases, none detected
 proteases, none detected

pH

4-6 (25 °C, 0.5 M in H2O)

mp

58 °C (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

sulfate (SO42-): ≤50 mg/kg

λ

0.5 M in H2O

UV absorption

λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01

Quality Level

200

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Other Notes

In the tailing of DNA - MnCl2 buffer recommended for dC and dG tailing; In reverse transcription of RNA with thermostable DNA polymerase

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Brain

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN3281
BCCM5039
BCCL6420
BCCH2663
BCCJ4597

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Nicholas Sofos et al.
Molecular cell, 79(5), 741-757 (2020-07-31)
Cmr-β is a type III-B CRISPR-Cas complex that, upon target RNA recognition, unleashes a multifaceted immune response against invading genetic elements, including single-stranded DNA (ssDNA) cleavage, cyclic oligoadenylate synthesis, and also a unique UA-specific single-stranded RNA (ssRNA) hydrolysis by the
T W Myers et al.
Biochemistry, 30(31), 7661-7666 (1991-08-06)
A recombinant DNA polymerase derived from the thermophilic eubacterium Thermus thermophilus (Tth pol) was found to possess very efficient reverse transcriptase (RT) activity in the presence of MnCl2. Many of the problems typically associated with the high degree of secondary
Terminal transferase: use of the tailing of DNA and for in vitro mutagenesis.
G Deng et al.
Methods in enzymology, 100, 96-116 (1983-01-01)
Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Asad A Aboud et al.
Neurotoxicology, 33(6), 1443-1449 (2012-10-27)
Manganese (Mn) is an environmental risk factor for Parkinson's disease (PD). Recessive inheritance of PARK2 mutations is strongly associated with early onset PD (EOPD). It is widely assumed that the influence of PD environmental risk factors may be enhanced by
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