Skip to Content
Merck

Key Documents

View All Documentation

A2729

Amisulpride

≥98% (HPLC), D2/D3 dopamine receptor antagonist , powder

Synonym(s):

4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide, DAN-2163, Deniban

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C17H27N3O4S
CAS Number:
71675-85-9
Molecular Weight:
369.48
NACRES:
NA.77
PubChem Substance ID:
24890689
UNSPSC Code:
12352200
EC Number:
275-831-7
MDL number:
MFCD00866691
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
Storage condition:
desiccated, protect from light
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Amisulpride, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated, protect from light

color

white

originator

Sanofi Aventis

storage temp.

2-8°C

SMILES string

O=C(NCC1CCCN1CC)C2=CC(S(=O)(CC)=O)=C(N)C=C2OC

InChI

1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)

InChI key

NTJOBXMMWNYJFB-UHFFFAOYSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR6(3362), HTR7(3363)

Application

Amisulpride has been used as a dopamine receptor inhibitor to study its effects on diabetic bone abnormalities in mice.

Biochem/physiol Actions

Amisulpride is a highly selective D2/D3 dopamine receptor antagonist and atypical antipsychotic.
Amisulpride is a substituted benzamide derivative. It has a higher affinity towards dopamine receptors in limbic structures than the striatal structures. Amisulpride has a therapeutic effect against schizophrenia.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Still not finding the right product?

Explore all of our products under Amisulpride

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000425775
0000425775
0000414873
0000414873
011M4727V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Amisulpride vs. risperidone in the treatment of acute exacerbations of schizophrenia
Peuskens J, et al.
Psychiatry Research, 88(2), 107-117 (1999)
Impaired gastric hormone regulation of osteoblasts and lysyl oxidase drives bone disease in diabetes mellitus
Daley E J, et al.
JBMR plus, 3(10), e10212-e10212 (2019)
J Peuskens et al.
Psychiatry research, 88(2), 107-117 (2000-01-06)
Amisulpride, a substituted benzamide with high selectivity for dopamine D3 and D2 receptors, was compared with the antipsychotic risperidone in patients with acute exacerbations of schizophrenia. The study was double-blind and involved 228 patients allocated, after a 3-6-day wash-out period
View All Related Papers