D1411
d-Desthiobiotin
≥98% (TLC)
Synonym(s):
5-Methyl-2-oxo-4-imidazolidinehexanoic acid
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About This Item
Empirical Formula (Hill Notation):
C10H18N2O3
CAS Number:
Molecular Weight:
214.26
PubChem Substance ID:
eCl@ss:
34058011
UNSPSC Code:
12352200
NACRES:
NA.25
EC Number:
208-566-2
MDL number:
Assay:
≥98% (TLC)
Form:
powder
Quality Segment
assay
≥98% (TLC)
form
powder
storage temp.
2-8°C
SMILES string
C[C@@H]1NC(=O)N[C@@H]1CCCCCC(O)=O
InChI
1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1
InChI key
AUTOLBMXDDTRRT-JGVFFNPUSA-N
Application
- to elute the precipitated proteins from the resin during coimmunoprecipitation
- to elute human Cdc45–MCM–GINS (CMG) helicase during chromatographic protein purification
- to elute the heterodimeric kinesin family member 3A/B (KIF3A/B) and kinesin associated protein 3 (KAP3)-binding APC armadillo (APCARM) domain during chromatographic purification
d-Desthiobiotin is used in affinity chromatography and protein chromatography. d-Desthiobiotin can be used for protein labeling, detection and isolation.
Biochem/physiol Actions
Desthiobiotin is a non-sulfur containing biotin derivative that binds less strongly to biotin-binding proteins and is easily dislocated by biotin.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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