Skip to Content
Merck

Key Documents

View All Documentation

E4786

Escitalopram oxalate

≥98% (HPLC), powder, serotonin reuptake inhibitor

Synonym(s):

S-(+)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate, S-(+)-Citalopram oxalate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C20H21FN2O · C2H2O4
CAS Number:
219861-08-2
Molecular Weight:
414.43
UNSPSC Code:
12352200
PubChem Substance ID:
329799062
NACRES:
NA.77
MDL number:
MFCD06407826
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
Storage condition:
desiccated
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Escitalopram oxalate, ≥98% (HPLC), powder

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to tan

solubility

DMSO: ≥15 mg/mL

originator

Forest Labs

storage temp.

2-8°C

SMILES string

OC(=O)C(O)=O.CN(C)CCC[C@]1(OCc2cc(ccc12)C#N)c3ccc(F)cc3

InChI

1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6)/t20-;/m0./s1

InChI key

KTGRHKOEFSJQNS-BDQAORGHSA-N

Gene Information

human ... SLC6A4(6532)

General description

Escitalopram oxalate is an anti-depressant. It is used to treat panic disorder and major depressive disorder(MDD).

Application

Escitalopram oxalate has been used as an antidepressant in rats exposed to chronic mild stress (CMS). It has also been used for scintillation proximity-based thermostability assay.

Biochem/physiol Actions

Escitalopram is a selective serotonin reuptake inhibitor (SSRI), the S-enantiomer and eutomer of citalopram.
Escitalopram oxalate is a selective serotonin reuptake inhibitor (SSRI); the S-enantiomer and eutomer of citalopram.

Features and Benefits

This compound was developed by Forest Labs. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Still not finding the right product?

Explore all of our products under Escitalopram oxalate

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000404022
0000404015
0000355582
0000307265
0000307265

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Escitalopram
Waugh J and Goa KL
CNS Drugs, 17(5), 343-362 (2003)
Modulation of the antioxidant nuclear factor (erythroid 2-derived)-like 2 pathway by antidepressants in rats
Martin-Hernandez D, et al.
Neuropharmacology, 103, 79-91 (2016)
Jasmin N Beaver et al.
Cells, 11(12) (2022-06-25)
Plasma membrane monoamine transporter (PMAT, Slc29a4) transports monoamine neurotransmitters, including dopamine and serotonin, faster than more studied monoamine transporters, e.g., dopamine transporter (DAT), or serotonin transporter (SERT), but with ~400-600-fold less affinity. A considerable challenge in understanding PMAT's monoamine clearance
View All Related Papers