Skip to Content
Merck

Key Documents

View All Documentation

O0257

Olvanil

powder

Synonym(s):

(N-Vanillyl)-9-oleamide, N-Vannilyloleoylamide

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C26H43NO3
CAS Number:
58493-49-5
Molecular Weight:
417.62
NACRES:
NA.77
PubChem Substance ID:
24897928
UNSPSC Code:
51111800
MDL number:
MFCD00673962
Form:
powder
Quality level:
200
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

powder

Quality Level

200

color

white to off-white

solubility

H2O: <0.2 mg/mL, DMSO: 20 mg/mL

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)NCc1ccc(O)c(OC)c1

InChI

1S/C26H43NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)27-22-23-19-20-24(28)25(21-23)30-2/h10-11,19-21,28H,3-9,12-18,22H2,1-2H3,(H,27,29)/b11-10-

InChI key

OPZKBPQVWDSATI-KHPPLWFESA-N

Gene Information

human ... TRPV1(7442)

Application

Olvanil has been used as a vanilloid (VR1) receptors agonist in rat VR1-transfected human embryonic kidney cells (rVR1-HEK) and dorsal root ganglion (DRG) cells to test its effect on calcium levels.

Biochem/physiol Actions

Olvanil is a vanilloid receptor agonist. It is an analog of capsaicin and is non-pungent. It is an orally active analgesic that alleviates pain by desensitizing nociceptors.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLBW9518
SLBV1845
SLBP4122V
SLBM2190V
SLBL6238V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Tamaki Hayase
BMC pharmacology, 11, 6-6 (2011-07-20)
The contributions of brain cannabinoid (CB) receptors, typically CB1 (CB type 1) receptors, to the behavioral effects of nicotine (NC) have been reported to involve brain transient receptor potential vanilloid 1 (TRPV1) receptors, and the activation of candidate endogenous TRPV1
Edmundo Castillo et al.
Biochemical and biophysical research communications, 356(2), 424-430 (2007-03-17)
Capsaicin (Cap) and its analogs (CAPanalogs) have diverse effects in sensory neurons including analgesia, implying they modulate other cellular targets besides the TRPV1 Cap receptor. Since Cap and CAPanalogs are not largely available and their chemical synthesis is cumbersome, they
Min-Goo Lee et al.
British journal of pharmacology, 146(4), 596-603 (2005-08-02)
Certain fatty acid amides such as anandamide (AEA) and olvanil are agonists for the transient receptor potential, vanilloid-1 (TRPV1) receptor, but have been found to activate TRPV1-containing C-fibers in some tissues but not others. We used extracellular recording and whole-cell
View All Related Papers