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T3146

Trimipramine maleate salt

≥98% (TLC), serotonin transport blocker, powder

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About This Item

Empirical Formula (Hill Notation):
C20H26N2 · C4H4O4
CAS Number:
521-78-8
Molecular Weight:
410.51
NACRES:
NA.77
PubChem Substance ID:
24278731
UNSPSC Code:
12352116
EC Number:
208-318-3
MDL number:
MFCD00082376
Assay:
≥98% (TLC)
Form:
powder
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Product Name

Trimipramine maleate salt, ≥98% (TLC), powder

Quality Segment

200

assay

≥98% (TLC)

form

powder

color

white to off-white

solubility

chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow

originator

Sanofi Aventis

storage temp.

2-8°C

SMILES string

OC(=O)\C=C\C(O)=O.CC(CN(C)C)CN1c2ccccc2CCc3ccccc13

InChI

1S/C20H26N2.C4H4O4/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;5-3(6)1-2-4(7)8/h4-11,16H,12-15H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key

YDGHCKHAXOUQOS-WLHGVMLRSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Application

Trimipramine maleate has been used to develop chiral separation methods using capillary electrophoresis4.

Biochem/physiol Actions

Antidepressant; serotonin transport blocker that also blocks norepinephrine uptake.

Preparation Note

Trimipramine maleate is soluble in chloroform at 50 mg/ml to yield a clear, colorless to faint yellow solution.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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