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Merck

ED

Ethylenediaminetetraacetic acid

purified grade, ≥98.5%, powder

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

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About This Item

Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS Number:
60-00-4
Molecular Weight:
292.24
NACRES:
NA.28
PubChem Substance ID:
24894707
eCl@ss:
39030907
UNSPSC Code:
12352116
EC Number:
200-449-4
MDL number:
MFCD00003541
Beilstein/REAXYS Number:
1716295

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InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

grade

purified grade

assay

≥98.5%

form

powder

reaction suitability

reagent type: chelator

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

Quality Level

200

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General description

Ethylenediaminetetraacetic acid (EDTA) is an affordable chelating agent. It is an aminopolycarboxylic acid and a hexadentate ligand and forms octahedral complex with cations. Ethylenediaminetetraacetic acid (EDTA) is not recommended for phytoremediation as it can leach into natural water resources. It is used in cosmetics and pharmaceutical industry. It triggers platelet aggregation in pseudothrombocytopenia. In chelation therapy, it elicits protection from oxidative damage during blood and lipid peroxidation and may be useful to treat cardiovascular and carbon tetrachloride induced liver fibrosis.

Application

Ethylenediaminetetraacetic acid may be used:
  • as a component of staining buffer
  • as buffer component for incubating epithelial cell adhesion molecule (EpCAM+) cells with fluorescein isothiocyanate (FITC)-conjugated antibody for cell sorting studies
  • for treating epithelial cells for isolation of mucosal myofibroblasts

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

target_organs

Respiratory Tract

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - STOT RE 2 Inhalation

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP1558
BCCN3742
BCCM5627
BCCL9246
BCCK7423

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The phenotypes of pluripotent human hepatic progenitors
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Environmental fate and microbial degradation of aminopolycarboxylic acids
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FEMS Microbiology Reviews, 25(1), 69-106 (2001)
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