01905
Adenosine 5′-diphosphate
≥95% (HPLC)
Synonym(s):
5′-ADP
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About This Item
Empirical Formula (Hill Notation):
C10H15N5O10P2
CAS Number:
Molecular Weight:
427.20
PubChem Substance ID:
eCl@ss:
32160414
UNSPSC Code:
41106305
NACRES:
NA.55
EC Number:
200-392-5
MDL number:
Beilstein/REAXYS Number:
67722
Assay:
≥95% (HPLC)
Form:
powder
Storage temp.:
−20°C
Quality Level
assay
≥95% (HPLC)
form
powder
impurities
≤15.0% water (KFT)
shipped in
dry ice
storage temp.
−20°C
SMILES string
Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
InChI
1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI key
XTWYTFMLZFPYCI-KQYNXXCUSA-N
Gene Information
human ... HSP90AA1(3320), P2RY1(5028)
Application
Adenosine 5′-diphosphate (5′-ADP or ADP) was used as a test compound for studying the endothelium-dependent vascular response in salt sensitive (DS) and salt resistant Dahl rats (DR). The product was used to study the different P2-purinergic receptor subtypes on canine vascular smooth muscle and endothelium.
Biochem/physiol Actions
Adenosine 5′-diphosphate induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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T F Lüscher et al.
Hypertension (Dallas, Tex. : 1979), 9(2), 157-163 (1987-02-01)
Experiments were designed to study endothelium-dependent responses in salt-sensitive (DS) and salt-resistant Dahl rats (DR). The rats were fed a low sodium (0.1% NaCl) or high sodium (8% NaCl) diet for 8 weeks. Blood pressure in DS fed a high
D A Houston et al.
The Journal of pharmacology and experimental therapeutics, 241(2), 501-506 (1987-05-01)
P2-Purinergic agonists can induce direct contractions in saphenous veins and endothelium-dependent relaxations in coronary arteries of the dog. For contractions, the rank order of agonist potency was alpha, beta-methylene-ATP much greater than ATP greater than ADP. For endothelium-dependent relaxation, the
R N Goldberg et al.
Biophysical chemistry, 40(3), 241-261 (1991-07-01)
The thermodynamic treatment of the disproportionation reaction of adenosine 5'-diphosphate to adenosine 5'-triphosphate and adenosine 5'-monophosphate is discussed in terms of an equilibrium model which includes the effects of the multiplicity of ionic and metal bound species and the presence