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Merck

SCP0103

Caspase Substrate

≥95% (HPLC), lyophilized

Synonym(s):

Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin, Z-YVAD-AFC, caspase-1 substrate VI

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About This Item

Empirical Formula (Hill Notation):
C39H40N5O11F3
Molecular Weight:
811.76
UNSPSC Code:
12352202
NACRES:
NA.32
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Product Name

Caspase Substrate, ≥95% (HPLC)

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥80%

storage condition

protect from light

storage temp.

−20°C

Gene Information

human ... CASP1(834)

Biochem/physiol Actions

Z-Tyr-Val-Ala-Asp-AFC, or Z-YVAD-AFC, is a fluorogenic substrate for caspase-1. The parent tetrapeptide is derived from the cleavage site for pro-interleukin b1, as the minimal sequence that caspase-1 recognizes.


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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