415324
N-Isopropylacrylamide
97%
Synonym(s):
NIPAM
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About This Item
Linear Formula:
H2C=CHCONHCH(CH3)2
CAS Number:
Molecular Weight:
113.16
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
218-638-5
MDL number:
Product Name
N-Isopropylacrylamide, 97%
InChI key
QNILTEGFHQSKFF-UHFFFAOYSA-N
InChI
1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
SMILES string
CC(C)NC(=O)C=C
assay
97%
bp
89-92 °C/2 mmHg (lit.)
mp
60-63 °C (lit.)
Quality Level
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Application
Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.
NIPAM can be used to prepare poly(NIPAM) based thermosetting polymers, which can be used for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.
General description
N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Meunier, F., Elaissari, A.
Surfactant Science Series, 115, 117-117 (2003)
Saunders, B.R.
Surfactant Science Series, 115, 419-419 (2003)
Temperature-responsive polymers for cell culture and tissue engineering applications
Switchable and Responsive Surfaces and Materials for Biomedical Applications, 32(5), 203-233 (2015)
Characterisation of biomedical coatings
Coatings for Biomedical Applications, 32(5), 176-220 (2012)
Bio-Instructive Scaffolds for Muscle Regeneration: NonCrosslinked Polymers
Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine, 34(9), 161-186 (2017)
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