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Merck

E-074

Estriol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C18H24O3
CAS Number:
50-27-1
Molecular Weight:
288.38
NACRES:
NA.24
PubChem Substance ID:
329798985
UNSPSC Code:
41116107
MDL number:
MFCD00003691

Key Documents

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InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

SMILES string

CC12CCC3C(CCc4cc(O)ccc34)C1CC(O)C2O

InChI key

PROQIPRRNZUXQM-ZXXIGWHRSA-N

grade

certified reference material

Quality Level

300

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

format

single component solution

storage temp.

−20°C

Related Categories

General description

Estriol is a metabolite of estradiol and the primary estrogen found in urine. Estriol levels in serum, plasma, or urine are measured by LC-MS/MS during pregnancy as part of maternal screens for Down-Syndrome-afflicted fetuses.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fuanglada Tongprasert et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 26(2), 146-149 (2012-09-20)
To compare the levels of maternal serum α-fetoprotein (AFP), unconjugated estriol (uE3) and free β-human chorionic gonadotropin (free β-hCG) between pregnancies with fetal Hb Bart's disease and unaffected pregnancies. 148 pregnancies at risk of fetal Hb Bart's disease scheduled for
Ioannis Papageorgiou et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(2), 281-290 (2012-12-12)
CYP3A activity is induced by approximately 2-fold during the third trimester of human pregnancy. Placental growth hormone (PGH), estrogens (primarily 17β-estradiol), cortisol, and progesterone have the potential to modulate CYP3A activity. Therefore, we determined whether the elevated plasma concentrations of
Swastika Surujlal-Naicker et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(1), 37-47 (2012-10-04)
Wastewater effluents have been documented as major contributors of hormone endocrine disrupting compounds (EDCs) in to the aquatic ecosystem. The need for rapid, simple and cost effective methods to detect these EDCs has increased. The use of Radio-immunoassays (RIA) were
Mitsuhiro Ueda et al.
Enzyme and microbial technology, 51(6-7), 402-407 (2012-10-09)
A protein with strong removal activity against the natural estrogen estriol was purified from a culture supernatant of Pleurotus eryngii var. tuoliensis C.J. Mou. The protein was characterized as a laccase and had a molecular mass of 60kDa on SDS-PAGE.
Sheikh O Jobe et al.
Hypertension (Dallas, Tex. : 1979), 61(2), 480-487 (2013-01-16)
Estrogens and estrogen metabolites have important functions in cardiovascular and other physiology, yet the patterns of estrogen synthesis, metabolism, and the individual plasma profile of estrogens and estrogen metabolites during human pregnancy as well as in preeclampsia remain undetermined. We
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