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Merck

C7515

Cannabidiol

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About This Item

Empirical Formula (Hill Notation):
C21H30O2
CAS Number:
Molecular Weight:
314.46
UNSPSC Code:
12352200
MDL number:
Form:
powder
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SMILES string

Oc1c(c(cc(c1)CCCCC)O)C2[C@@H](CCC(=C2)C)C(=C)C

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18?/m0/s1

InChI key

QHMBSVQNZZTUGM-ZENAZSQFSA-N

form

powder

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

storage temp.

2-8°C

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Biochem/physiol Actions

Not psychoactive in humans.

Other Notes

Major component of marijuana from C. sativa

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Alline Cristina Campos et al.
Psychopharmacology, 226(1), 13-24 (2012-09-26)
Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved
Michael G Serpell et al.
Journal of neurology, 260(1), 285-295 (2012-08-11)
Sativex is an endocannabinoid system modulator principally containing Δ(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD). During a 6-week randomised controlled trial, Sativex had a clinically relevant effect on spasticity associated with multiple sclerosis (MS). Patients self-titrated oromucosal Sativex to symptom relief or
Celia Oreja-Guevara
Revista de neurologia, 55(7), 421-430 (2012-09-27)
Spasticity remains a prevalent symptom in multiple sclerosis, with a significant associated disability and quality of life impairment. A significant improvement in therapy aimed at reducing multiple sclerosis relapses and modifying its course has been achieved in recent years. Both
Shaher Duchi et al.
Journal of neuroimmunology, 258(1-2), 32-40 (2013-03-23)
We investigated the efficiency of nasal drug administration as a new non-invasive treatment strategy for MS. Glatiramer Acetate (GA) and GA-Cannabidiol (CBD) combination administered in nasal delivery system (NDS) resulted in a statistically significant decrease of clinical scores and inflammatory
Amir Englund et al.
Journal of psychopharmacology (Oxford, England), 27(1), 19-27 (2012-10-09)
Community-based studies suggest that cannabis products that are high in Δ⁹-tetrahydrocannabinol (THC) but low in cannabidiol (CBD) are particularly hazardous for mental health. Laboratory-based studies are ideal for clarifying this issue because THC and CBD can be administered in pure

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