C8772
Cholera filtrate
lyophilized powder, bacterial sialidase receptor-destroying enzyme (RDE)
Synonym(s):
Cholera Filter
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.77
Product Name
Cholera filtrate, lyophilized powder
form
lyophilized powder
storage temp.
2-8°C
Quality Level
Related Categories
Application
Cholerafiltrate has been used as a receptor destroying enzyme (RDE): inhemagglutination inhibition assay of serum samples, in microneutralizationassay of mice serum samples, in hemagglutination inhibition assay to removenon-specific inhibitors from the cell culture supernatant samples
Biochem/physiol Actions
Cholera filtrate is a bacterial sialidase receptor-destroying enzyme (RDE) and may be used as crude neuraminidase. It may also be used in serological testing for influenza.
Disclaimer
For research use only. Not for use in diagnostic procedures.
General description
Cholera filtrate promotes the activation of adenylate cyclase. It does not affect the activity of cyclic adenosine monophosphate (cAMP) phosphodiesterase.
Other Notes
See a separate listing of neuraminidase for preparations showing higher activity.
Preparation Note
After reconstituting with 5ml sterile water, it will contain 0.01% MIT as preservative.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
Daniela M, et al.
Nature Communications (2024)
WHO Tech Rep. Serv.
WHO Expert Committee on Influenza, 64 (1953)
Yao Lu et al.
Vaccine, 38(10), 2387-2395 (2020-02-06)
The highly pathogenic avian influenza (HPAI) H5N1 viruses and their spillover into the human population pose substantial economic and public health threats. Although antiviral drugs have some effect in treating influenza infection, vaccination is still the most effective intervention to
A V Kornev et al.
Biulleten' eksperimental'noi biologii i meditsiny, 88(10), 414-416 (1979-10-01)
An in vitro model using homogenates of the rat intestine and liver for studying the V. Cholerae culture filtrate effect on the adenylate cyclase system is proposed. Optimal conditions for the adenylate cyclase functioning have been investigated for this model.
Maria Zimmermann et al.
Frontiers in immunology, 10, 829-829 (2019-05-02)
Determining antigen specificity is vital for understanding B cell biology and for producing human monoclonal antibodies. We describe here a powerful method for identifying B cells that recognize membrane antigens expressed on cells. The technique depends on two characteristics of
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