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Merck

131601P

Avanti

Egg PC (95%)

Avanti Research - A Croda Brand

Sinónimos:

L-α-phosphatidylcholine (95%) (Egg, Chicken)

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Número CAS:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (131601P-1g), pkg of 10 × 1 g (131601P-10g), pkg of 5 × 1 g (131601P-5g)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

General description

l-α-phosphatidylcholine constitutes 20% of the total phospholipids in chicken egg. It has palmitic acid (16:0) and oleic acid (18:1) in at sn-1 and sn-2 positions, respectively.
Egg PC (95%) is a mixture of 16 to 22 carbon atoms long acyl chain containing multiple double bonds. Major portion (98%) of phospholipid contains a single saturated and unsaturated chain.
Egg PC is a further purification of Total Egg Extract. This Natural Lipid is a mixture, and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.

Application

Egg PC (95%) has been used for the reconstitution of purified Kv1.3 into liposomes.
Egg PC (95%) has been used in the synthesis of high-density lipoprotein (HDL) based nanoparticle for nerve growth factor (NGF) encapsulation. It has also been used in the proteoliposome preparation.

Biochem/physiol Actions

Egg PC in its saturated form favors inhibition of cholesterol absorption. It is used in lipid preparation and liposomes for biophysical studies. Egg PC contributes cardiovascular disease (CVD) risk by acting as a substrate for microbes leading to of trimethylamine N-oxide (TMAO) synthesis.

Packaging

125 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-5g)
250 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-10g)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1. 3
Bednenko J, et al.
MAbs, 10(4), 636-650 (2018)
Preparation and characterization of novel hdl-mimicking nanoparticles for nerve growth factor encapsulation
Zhu, Jing and Dong, Xiaowei
Journal of Visualized Experiments, (123), e55584-e55584 (2008)
Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation
Perez C, et al.
Structure (2019)