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840037P

Avanti

16:0 PS

Avanti Research™ - A Croda Brand

Sinónimos:

1,2-dihexadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DPPS; PS(16:0/16:0); 110668

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Fórmula empírica (notación de Hill):
C38H73NO10PNa
Número CAS:
145849-32-7
Peso molecular:
757.95
MDL number:
MFCD00466991
UNSPSC Code:
51191904
NACRES:
NA.25
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description

1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840037P-10mg), pkg of 1 × 200 mg (840037P-200mg), pkg of 1 × 25 mg (840037P-25mg), pkg of 1 × 500 mg (840037P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C38H74NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)46-31-34(32-47-50(44,45)48-33-35(39)38(42)43)49-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h34-35H,3-33,39H2,1-2H3,(H,42,43)(H,44,45);/q;+1/p-1/t34-,35+;/m1./s1

InChI key

GTLXLANTBWYXGW-CEGNZRHUSA-M

General description

Phosphatidylserine (PtdSer) is an anionic phospholipid abundantly present in the eukaryotic cell. 10% of the total cellular lipid consists of phosphatidylserine. O‐phospho‐L‐serine is a heat‐stable substrate.

Application

16:0 PS may be used in liposome flotation assay to measure its interactions between purified dynamin related protein 1 (Drp1) and as a component in the lipid mixtures to prepare lipid monolayers. It has also been used to prepare liposomes by the lipid film hydration method.
16:0 PS has been used in the assay to measure interactions between purified dynamin-related protein 1 (Drp1) and synthetic liposomes.

Biochem/physiol Actions

Phosphatidylserine (PtdSer) participates in various intracellular signaling pathways. It also play a major role in apoptosis and blood clotting.

Packaging

20 mL Clear Glass Screw Cap Vial (840037P-200mg)
30 mL Amber Wide Mouth Bottle with Screw Cap (840037P-500mg)
5 mL Amber Glass Screw Cap Vial (840037P-10mg)
5 mL Amber Glass Screw Cap Vial (840037P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Clase de almacenamiento

11 - Combustible Solids

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Assay to Measure Interactions between Purified Drp1 and Synthetic Liposomes
Adachi Y, et al.
Bio-protocol, 7(9) (2017)
Chelsea A Kraynak et al.
Acta biomaterialia, 108, 250-260 (2020-04-07)
Macrophages play a critical role in the initiation, maintenance, and resolution of inflammation because of their diverse and plastic phenotypic responses to extracellular stimuli. Inflammatory stimuli drive the recruitment and activation of inflammatory (M1) macrophages, capable of significant cytokine production
Condensation of Model Lipid Films by Cholesterol: Specific Ion Effects
Martimathin-MA, et al.
Coatings, 9(8), 474-474 (2020)
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