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Merck

840435P

Avanti

12:0 PG

Avanti Research - A Croda Brand

Sinónimos:

1,2-didodecanoyl-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DLPG; PG(12:0/12:0)

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Fórmula empírica (notación de Hill):
C30H58O10PNa
Número CAS:
Peso molecular:
632.74
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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description

1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (840435P-200mg), pkg of 1 × 25 mg (840435P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC)OCC(O)CO

InChI

1S/C30H59O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-29(33)37-25-28(26-39-41(35,36)38-24-27(32)23-31)40-30(34)22-20-18-16-14-12-10-8-6-4-2;/h27-28,31-32H,3-26H2,1-2H3,(H,35,36);/q;+1/p-1/t27?,28-;/m1./s1

InChI key

CIRSYGHBBDDURM-AMRYRHMLSA-M

General description

Phosphatidylglycerol (PG) is one of the most important lipid, found in Gram-positive bacteria. It has odd-numbered branched-chain fatty acids as acyl chains. This phospholipid is ubiquitously present in the membranes of several organisms. 12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol)/DLPG) is an anionic phospholipid. It is an anionic analogue of the zwitterionic phospholipid, dilauroyl phosphatidylcholine (DLPC).

Application

12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol)) has been used in monomolecular films as representative lipid component of eukaryotic membranes to study the generality of the non-steroidal anti-inflammatory drug (NSAID)-related effect. It may also be used:
  • in the preparation of liposomes for PagP folding assays
  • as a component in pyrene labeleld liposomes
  • to construct liposome/lipid vesicle

Biochem/physiol Actions

Phosphatidylglycerol (PG) is known to participate in photosynthesis.

Packaging

5 mL Amber Glass Screw Cap Vial (840435P-200mg)
5 mL Amber Glass Screw Cap Vial (840435P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Clase de almacenamiento

11 - Combustible Solids



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Lloyd Ryan et al.
The Journal of biological chemistry, 288(28), 20162-20172 (2013-06-06)
Antimicrobial or host defense peptides are innate immune regulators found in all multicellular organisms. Many of them fold into membrane-bound α-helices and function by causing cell wall disruption in microorganisms. Herein we probe the possibility and functional implications of antimicrobial
FATS vert Occurrence
Encyclopedia of food sciences and nutrition, 2293-2296 (2003)
Gerardino D'Errico et al.
Biochimica et biophysica acta, 1778(12), 2710-2716 (2008-08-19)
There is mounting evidence that the lipid matrix of neuronal cell membranes plays an important role in the accumulation of beta-amyloid peptides into senile plaques, one of the hallmarks of Alzheimer's disease (AD). With the aim to clarify the molecular