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Merck

858143P

Avanti

18:1 Lyso PS

Avanti Research - A Croda Brand

Sinónimos:

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(18:1(9Z)/0:0); 18:1 LPS; C18:1 LPS; 110726

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Fórmula empírica (notación de Hill):
C24H45NO9PNa
Número CAS:
Peso molecular:
545.58
UNSPSC Code:
51191904
NACRES:
NA.25
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description

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium salt)

assay

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (858143P-10mg), pkg of 1 × 100 mg (858143P-100mg), pkg of 1 × 25 mg (858143P-25mg), pkg of 1 × 5 mg (858143P-5mg), pkg of 1 × 50 mg (858143P-50mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI key

ULNYNKJABITZRB-UZADSWFSSA-M

Application

18:1 Lyso PS has been used:
  • for the preparation of phospholipid vesicles
  • to study its effects on nerve growth factor (NGF)-induced mitogen-activated protein kinase (MAPK) and serine/threonine-protein kinase (Akt) signals
  • to prevent the lack of de novo synthesis of phosphatidylserine (PS) in Golgi apparatus

Packaging

5 mL Clear Glass Sealed Ampule (858143P-100mg)
5 mL Clear Glass Sealed Ampule (858143P-10mg)
5 mL Clear Glass Sealed Ampule (858143P-25mg)
5 mL Clear Glass Sealed Ampule (858143P-50mg)
5 mL Clear Glass Sealed Ampule (858143P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid
Varela Chavez C, et al.
Cellular Microbiology, 17(10), 1477-1493 (2015)
Suriakarthiga Ganesan et al.
Traffic (Copenhagen, Denmark), 20(3), 226-245 (2018-12-21)
Diacylglycerol (DAG) is a key signaling lipid and intermediate in lipid metabolism. Our knowledge of DAG distribution and dynamics in cell membranes is limited. Using live-cell fluorescence microscopy we investigated the localization of yeast cytosolic-facing pools of DAG in response
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple