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Merck

860060P

Avanti

Ganglioside GD3 (Bovine Milk)

Avanti Research - A Croda Brand

Sinónimos:

110954

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Número CAS:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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description

GD3 Ganglioside (Milk, Bovine-Ammonium Salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860060P-1mg), pkg of 1 × 5 mg (860060P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

lipid extracts
sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO[C@@]4(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C4)[C@@](NC(

General description

Gangliosides are glycosphingolipids containing a hydrophobic ceramide and hydrophilic oligosaccharide chain. They are found in various tissues and fluids in vertebrates, especially in human brain and bovine milk. The most common gangliosides in milk are 2NeuAc−2Hex−Cer (GD3) and NeuAc−2Hex−Cer (GM3).

Application

Ganglioside GD3 (Bovine Milk) is suitable as a lipid standard in Fourier-transform ion cyclotron resonance (FTICR) mass spectrometric analysis and liquid chromatography−mass spectrometry (LC-MS/MS) data analysis.

Biochem/physiol Actions

Gangliosides are involved in neuronal development, neuropathologic processes, receptor interactions with protein hormones, interferon, fibronectin and toxins from bacteria, They are also essential for the development of intestinal immunity by producing intestinal IgA and cytokine.

Packaging

5 mL Amber Glass Screw Cap Vial (860060P-1mg)
5 mL Amber Glass Screw Cap Vial (860060P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available



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Certificados de análisis (COA)

Lot/Batch Number

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Variation of the ganglioside compositions of human milk, cow?s milk and infant formulas
Pan X L, et al.
Early Human Development, 57(1), 25-31 (2000)
The role of dietary gangliosides on immunity and the prevention of infection
Rueda R
The British Journal of Nutrition, 98(S1), S68-S73 (2007)
Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain
Zhang Y, et al.
Scientific Reports, 6, 25289-25289 (2016)