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Permítanos ayudarleNombre del producto
16:0 PEG2000 PE, Avanti Research™ - A Croda Brand 880160P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (880160P-1g), pkg of 1 × 200 mg (880160P-200mg), pkg of 1 × 25 mg (880160P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 880160P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]
InChI key
CNBWQQBZNGZZDB-KTYSZVIQSA-N
General description
16:0 PEG2000 PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DPPEmPEG2000), is a polyethylene glycol (mPEG) phospholipid conjugate. Incorporation of PEG-modified lipid conjugates in liposomes facilitates the formation of sterically stabilized liposomes (SSL), which have low reticuloendothelial system (RES) uptake and prolonged circulation lifetimes. These properties aid the PEGylated liposomes to spontaneously deliver drugs to targeted cells.
Application
16:0 PEG2000 PE, or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used in liposome preparation. It has also been used in preparation of tripeptide arginine-glycine-aspartic acid magnetoliposomes (RGD-MLPs) and poly(ethylene glycol) (PEG)- MLPs.
Packaging
20 mL Clear Glass Screw Cap Vial (880160P-1g)
5 mL Amber Glass Screw Cap Vial (880160P-200mg)
5 mL Amber Glass Screw Cap Vial (880160P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Clase de almacenamiento
11 - Combustible Solids
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Joan Estelrich et al.
ACS omega, 2(10), 6544-6555 (2018-07-20)
We tested the targeting efficiency of magnetoliposomes (MLPs) labeled with tripeptide arginine-glycine-aspartic acid (RGD) on two types of cells: HeLa cells expressing RGD receptors and 3T3 cells lacking RGD receptors. The targeting ability of RGD-MLPs was compared to that of
D Kirpotin et al.
FEBS letters, 388(2-3), 115-118 (1996-06-17)
Plasma-stable liposomes (100 nm) were prepared from dioleoylphosphatidylethanolamine (DOPE) and 3-6 mol% of a new disulfide-linked poly(ethylene glycol)-phospholipid conjugate (mPEG-DTP-DSPE). In contrast to similar preparations containing non-cleavable PEG-phospholipid conjugate, thiolytic cleavage of the grafted polymer chains facilitated rapid and complete
Ilaria Arduino et al.
International journal of pharmaceutics, 583, 119351-119351 (2020-04-28)
Here, polyethylene glycol (PEG)-stabilized solid lipid nanoparticles (SLNs) containing Pt(IV) prodrugs derived from kiteplatin were designed and proposed as novel nanoformulations potentially useful for the treatment of glioblastoma multiforme. Four different Pt(IV) prodrugs were synthesized, starting from kiteplatin by the