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Merck

V-007

O-Desmethylvenlafaxine solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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Fórmula empírica (notación de Hill):
C16H25NO2
Número CAS:
93413-62-8
Peso molecular:
263.38
NACRES:
NA.24
PubChem Substance ID:
329828919
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00871934

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InChI key

KYYIDSXMWOZKMP-UHFFFAOYSA-N

InChI

1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3

SMILES string

OC1=CC=C(C(CN(C)C)C2(O)CCCCC2)C=C1

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

300

Gene Information

human ... SLC6A2(6530), SLC6A4(6532)

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General description

An analytical reference standard applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as urine drug testing, forensic analysis, or clinical toxicology. Also known as desvenlafaxine, O-desmethylvenlafaxine is an SNRI antidepressant marketed under the trade name Pristiq® for the treatment of depression. O-desmethylvenlafaxine is also a major urinary metabolite of venlafaxine, an SNRI antidepressant sold as Effexor® or Efexor and used to treat major depressive disorder, generalized anxiety disorder, and other anxiety disorders associated with depression.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Effexor is a registered trademark of American Home Product Corp.
Pristiq is a registered trademark of Wyeth LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Clase de almacenamiento

3 - Flammable liquids

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

target_organs

Eyes,Central nervous system

wgk

WGK 2

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Paola C Rúa-Gómez et al.
Chemosphere, 90(6), 1952-1959 (2012-11-20)
The photodegradation and biotic transformation of the pharmaceuticals lidocaine (LDC), tramadol (TRA) and venlafaxine (VEN), and of the metabolites O-desmethyltramadol (ODT) and O-desmethylvenlafaxine (ODV) in the aquatic environmental have been investigated. Photodegradation experiments were carried out using a medium pressure
Anita H Clayton et al.
The journal of sexual medicine, 10(3), 768-776 (2012-08-22)
The symptoms of major depressive disorder (MDD) include sexual dysfunction, but antidepressant pharmacotherapies are also associated with treatment-emergent sexual dysfunction. These secondary and post hoc analyses evaluated sexual functioning in employed adult outpatients with MDD treated with desvenlafaxine (administered as
Thomas Guttuso
Maturitas, 72(1), 6-12 (2012-03-02)
Although many non-hormonal compounds have shown statistically significant benefit over placebo in hot flash randomized controlled trials (RCTs), these studies have varied considerably in basic methodology making it challenging to deduce which compounds have the greatest potential to provide clinically
Paola C Rúa-Gómez et al.
Journal of environmental monitoring : JEM, 14(5), 1391-1399 (2012-03-27)
The presence of the anesthetic lidocaine (LDC), the analgesic tramadol (TRA), the antidepressant venlafaxine (VEN) and the metabolites O-desmethyltramadol (ODT) and O-desmethylvenlafaxine (ODV) was investigated in wastewater treatment plant (WWTP) effluents, in surface waters and in groundwater. The analytes were
S Unterecker et al.
Pharmacopsychiatry, 45(6), 229-235 (2012-03-20)
Venlafaxine (VEN) is a modern antidepressant which exerts both serotonin and norepinephrine reuptake inhibition. In this study we examined the influence of age, sex, smoking, and co-medication on serum levels of VEN and its metabolite O-desmethylvenlafaxine (ODVEN) in patients treated
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