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Merck

1.03669

Glicina

granulated, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

Sinónimos:

Glicocola, Ácido aminoacético, Ácido aminoetanoico

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About This Item

Fórmula lineal:
NH2CH2COOH
Número CAS:
Peso molecular:
75.07
EC Index Number:
200-272-2
UNSPSC Code:
12352209
Beilstein/REAXYS Number:
635782
MDL number:

Nombre del producto

Glicina, granulated, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

agency

BP
ChP
JP
Ph. Eur.
USP

vapor pressure

0.0000171 Pa ( 25 °C)

description

granulated EMPROVE® EXPERT Ph.Eur.,BP,JP,USP

product line

EMPROVE® EXPERT

assay

99.0-101.0% (calculated on dried substance, perchloric acid titration)

form

granular

technique(s)

inhibition assay: suitable

pH

5.9-6.4 (20 °C, 50 g/L in H2O)

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

density

1.161 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

2-30°C

Quality Level

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Biochem/physiol Actions

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Application

Glycine in general is widely used in the biopharma industry as a stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine granulated Emprove® Expert is especially suitable for high-risk applications.

General description

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing processes and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, granulated glycine is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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