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AB4350

Anti-PRDM14 Antibody

Name: Anti-PRDM14 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Sinónimos:

PR domain zinc finger protein 14, PR domain-containing protein 14

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UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

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Propiedades

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, mouse, human

technique(s)

western blot: suitable

NCBI accession no.

NP_078780

UniProt accession no.

Q9GZV8

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PRDM14(63978)

Descripción

General description

PR domain proteins (PRDMs) have been associated with many types of human cancers. PRDM14 was found to be up-regulated in breast cancer cells. The expression of PRDM14 to breast cancer cells actually increased cell proliferation and decreased the effect of chemotherapeutic drugs, while down-regulation of PRDM14 did the opposite. In addition to breast cancer, PRDM14 has recently been linked to non-small cell lung cancer development. PRDM14 also seems to play a role in the preservation of the self-renewal of human embryonic stem cells and transcriptional regulation.

~62 kDa observed

Immunogen

GST-tagged recombinant protein corresponding to the N-terminus of human PRDM14.

Application

This Anti-PRDM14 Antibody is validated for use in WB for the detection of PRDM14.

Biochem/physiol Actions

This antibody recognizes the N-terminus of PRDM14.

Analysis Note

Evaluated by Western Blot in human lung tissue lysate.

Western Blot Analysis: A 1:1000 dilution of this antibody detected PRDM14 in 10 µg of human lung tissue lysate.

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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c